On 11/19/2007 I was put under anathesia and had 20Depomedrol with lidocaine injected into c2-c3,c3-c4andc4-c5 for right sided neck pain from a 4 year old injury(total 60 depomedrol). Since injections pain much worse left side of neck now affected and less movement. However the worst thing that has happened is that I developed SEVERE depression and SEVERE anxiety( I do have a history of panic attacks( which I managed with coping skills ( this anxiety is way too high for the coping skills!and was feeling a little sad prior to injections( over life stress) However, nothing like this! I felt confused, forgetful, underwater and a fog between me and other people,hopeless, had wierd thoughts no feelings of joy or affection fear of being put in psych. unit( I know that would only scare me more and make me feel worse).I also feel horrible physically which is slightly improving. I developed boils, fatigue,nausea, chills no appetite muscle spasms, crying jags etc. It all began 2 days after the injections. I went to psychiatrist( highly recommended one- he is a clinical pharmacologist)) who put me on Seraquel even though I am not bipolar or psychotic, he says it is now being used to treat depression and anxiety. Last night 1/31 was the first night I took 300.The drug seems to be helping some but thoughts of ending it all are a little more comforting and still have wierd ,scary thoughts. I am just not myself at all. He says suicidal thoughts not drug related just symptoms moving around. I would like to know what you know about the depomedrol effecting me both physically and mentally. Someone shared info. with me saying it could have shut down my adrenal system . I am hypothyroid- used to have Graves Disease, am very sensitive to many medications( paxil=hand tremors, zoloft and celexa= diarrhea). Can't take Benadryl,codeine, atenalol, naldecon, prevascid)Neurosurgeon wants me to take celebrex for neck pain but I am afraid to take that. Also wants bone scan but I don't want to get dye injected at this point. Please help with advice on the depomedrol, anxiety and depression and neck pain. Also could those injections have affected me neurologically.because of being at c2c3? I did not feel confused or forgetful until anxiety and depression kicked in. I am very frightened and feel like this is a viscious cycle I can't get out of.Also is seraquel being used for people who are not bipolar or psychotic and at a dose of 300?It makes me very tired he says that should pass if it doesn't it then is not the drug for me. I am afraid to drive and feel very isolated. I am also on a very small dose of Xanax (.125 twice a day ) if I feel I need it, My primary physician has been of no help and the doctor who injected me does not want to acknowledge the increased neck pain or reaction to steroids. In fact he recommended an epidural or burn the nerve root. Neurosugeon says do physical therapy with myofascial pain release. Pain specialist says therapy makes facet joint injuries worse. Please Help!