Depression Community
How do I make the switch from Cymbalto to Prozac
About This Community:

A community of people suffering from Depression to guide and support your health journey. Ask a question, join a conversation, share experiences: symptoms, counseling, and other management.

Font Size:
A
A
A
Background:
Blank
Blank
Blank
Blank Blank

How do I make the switch from Cymbalto to Prozac

I want to know if anyone has switched safely from Cymbalta to Prozac? I was previously on Prozac for a couple of years and my dr. & I believed that it had stopped being as effective. I changed to Cymbalta with great results. However, I am starting to believe that it is no longer working and am considering changing back to Prozac.

Has anyone else had trouble with the drugs effects tapering off like that? And if so, how do I go about safely making the change?
Tags: prozac
Related Discussions
4 Comments Post a Comment
Blank
1666691_tn?1303757948
it can happen yes that these kind of meds stop working for you.why go back to prozac if it didnt work for you anymore?I believe if theyre both ssri's you can swith from one day to the next.lily
Blank
Avatar_m_tn
By rxlynn

To agree with lilymoon, and add some 2 cents, the literature is filed with studies re: antidepressants which were once effective sometimes seem to wear off.  As lilymoon notes, both Prozac and Cymbalta are SSRI's.  Prozac is longer acting (though both are taken daily); this is what is known as the half-life of a drug.  For Prozac, the half life is 4-6 days. (it generally takes 5 half lives for a drug to clear your body); for Cymbalta the half life is 12 hours.  So theoretically Cymbalta would be out of your system in about 3 days.  I always advocate letting your doctor know about changing, especially since they should have it in your records (or at least let their staff know so the Dr. can talk to you).
Hope this was helpful to you.  
Blank
Avatar_f_tn
Talk to your doctor about how best to do this.
Blank
Avatar_f_tn
I changed from cymbalta to prozac.  Cymbalta has terrible side effects and withdrawal symptoms.  You must use caution when changing.  With my doctor's guidance (and my research) this is what i did to make the change:  For the first three days, remove two (2) grains of medication from the capsule.  The next three (3) days, remove 4 grains from the capsule.  The next three (3) days, remove 6 grains from the capsule; and so on until you are off the medication.  It is NOT out of your system in 3 days.  During this time, I also started Prozac at a low dose and it was gradually increased.  Cymbalta will be in your system for a while after you have finised so do not be surprised if you still have effects from it until it is clear.  In the past I had been on prozac for 5 years but found this did not work for me again.  After much research and with my doctor I switched to Pristiq.  So far, I am much happier.  It does not seem to help with anxiety but overall, I am glad I tried it.  Minimal side effects for me in the beginning.  But at the end of the 2nd week (as most other individuals mentioned) it seemed to kick in and I could feel a decided difference.  Good luck.  
Blank
Post a Comment
To
Recent Activity
1236893_tn?1408490528
Blank
Individuals with social phobia have...
15 hrs ago by gymdandee
Avatar_m_tn
Blank
ScorpionKing8 commented on HIV and ORAL SEX: The...
Jul 02
1302038_tn?1431717453
Blank
TinaR10 commented on TinaR10's status
Jul 01
Blank
Mood Tracker
Track your mood over time
Start Tracking Now
Top Mood Disorders Answerers
1551327_tn?1414146344
Blank
Bubulous
Tompkinsville, KY
1110049_tn?1409405744
Blank
4Maddie44
Dorset, United Kingdom
Avatar_f_tn
Blank
Crystal413
VA
Avatar_f_tn
Blank
ggreg
NC
Avatar_m_tn
Blank
DYSLEXIC
notts, United Kingdom
Depression Community Resources
RSS Expert Activity
233488_tn?1310696703
Blank
Marathon Running Done Over Many Yea...
May 21 by John C Hagan III, MD, FACS, FAAOBlank
233488_tn?1310696703
Blank
New Article on Multifocal IOL vs &q...
May 21 by John C Hagan III, MD, FACS, FAAOBlank
748543_tn?1371753642
Blank
TMJ/TMJ The Connection Between Teet...
Jan 27 by Hamidreza Nassery , DMD, FICOI, FAGDBlank
Top Mood Disorders Answerers
1551327_tn?1414146344
Blank
Bubulous
Tompkinsville, KY
1110049_tn?1409405744
Blank
4Maddie44
Dorset, United Kingdom
Avatar_f_tn
Blank
Crystal413
VA
Avatar_f_tn
Blank
ggreg
NC
Avatar_m_tn
Blank
DYSLEXIC
notts, United Kingdom