If Effexor have been successful in the past and you want to avoid sexual side-effect but want to try a new antidepressant than I highly suggest Cymbalta or Pristiq (the new Effexor).
Please address your medication change, dosage or schedule with a qualified physician.
M4
Thanks for your help. I have decided to ditch my psychiatrist and the tablets and wean myself of the Wellbutrin using Prozac. On day three now and already feeling heaps better but with a cloudy head. Problem is I don't want to stay on the Prozac as it previoiusly stopped working for me (altho' was great at first) and also played hell with my sex life! Any ideas for a replacement? - effexor was also successful in the past. I see from your previous posts that you seem to be pretty knowledgeable about various medications.
The probability of being irritable on this drug are higher than any other antidepressant due to its highly stimulating effect.
A NDRI like Wellbutrin alone cannot really take care of your depression if serotonin is involved in your depression too this is why they use Wellburtrin as a combo most of the time with a SSRI.
M4