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Prozac + Alcohol
I have been on 20 mg of Prozac for over 6 months now.  When I started the Prozac, I also began psychotherapy and quit drinking alcohol.  From time to time, over the first few months I would have a glass of wine, but each time, I would experience a mood swing (irritability, negativity, depression, and all the other fun stuff I was dealing with before I got on Prozac).  

A couple of weeks ago, my therapist and I decided I might be ready to try a glass of wine or two again (it had been 3 months and I had made a lot of progress).  I thought it went really well, and I have had a glass of wine or two a few times a week over the past couple weeks.  But now, for the past week, I am suffering from excruciating headaches, mood swings, anxiety, over-emotionalness, etc. Needless to say, when I finally made the connection yesterday (don't ask why it took a week to realize why I'd slipped back into my pre-prozac craziness), I decided to put away the alcohol for the foreseeable future.

My question is whether anyone else has experienced bad headaches (or other unpleasant side-effects) from the combo of Prozac and a very moderate amount of drinking?
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1416835 tn?1295814883
I've never been on Prozac but the group of drugs it belongs to (SSRIs) often cause problems with alcohol.  I was on one kind (citalopram/celexa) where I could have a glass sometimes but most of the time absolutely NOT.  I'd have horrible stomach pain and headaches and mood swings and extreme drowsiness.  Now I'm on another similar kind of drug (mirtazapine, NSRI) where I can have maybe a glass.  
My friend is on an SSRI and can't drink at all because of what it does to her.  Other people can have some alcohol and it's no trouble.  It depends on how you as an individual react to it.  
I'd advise just leaving off the alcohol altogether.  It's not worth it.  
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