Depression Community
Prozac and Klonopin mixed together?
About This Community:

A community of people suffering from Depression to guide and support your health journey. Ask a question, join a conversation, share experiences: symptoms, counseling, and other management.

Font Size:
A
A
A
Background:
Blank
Blank
Blank
Blank Blank

Prozac and Klonopin mixed together?

Hello

I recently (3 weeks ago) switched from 40mg Paxil/day to 20mg Prozac/day.  The first 3 weeks went fine with expected dizziness and nausea.  But the past few days I've been experiencing depression.

1)  Is this normal?  Perhaps the paxil is out of my system and the prozac has not kicked in yet?  It's a bit weird because I was not depressed during the last 3 weeks.  I hope this goes away..

2) How long does prozac take to fully "kick in" ?

3) I also take 2x .5mg klonopin a day as needed (as I did with the paxil) but I was just reading this on wikipedia..

http://en.wikipedia.org/wiki/SSRI#Contraindications_and_drug_interaction

It says that benzodiazepines like alprazolam (Xanax) or diazepam (Valium) (klonopin is also a benzo) along with SSRIs (paxil/prozac) may increase blood levels and risk of toxicities.

IF this is true

4) Why am I prescribed Klonopin with the Prozac (and previously the Paxil?)  I have had no problems with mixing the two together but I'm curious as to why it would say that in wikipedia.

Thanks!
Related Discussions
2 Comments Post a Comment
Blank
Avatar_f_tn
Are you able to call a pharmacist now? They will be able to answer better than someone here.
Blank
Avatar_m_tn
Hopefully you followed the sensible advice to ask a pharmacist. If you didn't, 'ballpark' answers would be:

1) Paxil (Paroxetine) is well-known to have unpleasant symptoms as part of a discontinuation syndrome. 40mg daily is a significant dose and one would expect to have difficult experiences upon changing or stopping it. However, three weeks is a long-time, it's possible your mood is dropping and worth discussing this with your doctor.

2) Prozac (Fluoxetine) has a very long half-life, possibly up to eight weeks, and so does take much longer than most SSRI's to 'kick in'. Also, it's thought any individual anti-depressant will only produce symptom relief in about two-thirds of depressed individuals who take it. Again, perhaps speak with your prescriber.

3) & 4) Wikipedia does not give 'ex cathedra' advice and you should be critical of anything you read there. Klonopin (Clonazepam) is a powerful benzo; 1mg is roughly equivalent to 10mg of Valium (Diazepam). All drugs have unwanted effects as well as therapeutic ones and mixing drugs will almost always carry a possibility of interaction. However, if this interaction is rare, your prescriber has presumably decided that the benefits of you taking Klonopin outweigh the risks. Yet again, you need to discuss this with your doctor.

Good luck!
Blank
Post a Comment
To
Recent Activity
1174869_tn?1333665348
Blank
Mood Tracker: August 21, 2015
7 hrs ago by char1234vass
693583_tn?1417464176
Blank
lboogie7729 is hanging in there Comment
12 hrs ago
2020005_tn?1417986816
Blank
KTowne commented on renae176's status
15 hrs ago
Blank
Mood Tracker
Track your mood over time
Start Tracking Now
Top Mood Disorders Answerers
1551327_tn?1414146344
Blank
Bubulous
Tompkinsville, KY
Avatar_f_tn
Blank
Crystal413
VA
Avatar_f_tn
Blank
ggreg
NC
1257808_tn?1322765815
Blank
MR_WHY
Other
Avatar_f_tn
Blank
JE55LEW
MANCHESTER, United Kingdom
Depression Community Resources
RSS Expert Activity
233488_tn?1310696703
Blank
Marathon Running Done Over Many Yea...
May 21 by John C Hagan III, MD, FACS, FAAOBlank
233488_tn?1310696703
Blank
New Article on Multifocal IOL vs &q...
May 21 by John C Hagan III, MD, FACS, FAAOBlank
748543_tn?1371753642
Blank
TMJ/TMJ The Connection Between Teet...
Jan 27 by Hamidreza Nassery , DMD, FICOI, FAGDBlank
Top Mood Disorders Answerers
1551327_tn?1414146344
Blank
Bubulous
Tompkinsville, KY
Avatar_f_tn
Blank
Crystal413
VA
Avatar_f_tn
Blank
ggreg
NC
1257808_tn?1322765815
Blank
MR_WHY
Other
Avatar_f_tn
Blank
JE55LEW
MANCHESTER, United Kingdom