Depression Community
Switch from Effexor back to Paxil without tapering?
About This Community:

A community of people suffering from Depression to guide and support your health journey. Ask a question, join a conversation, share experiences: symptoms, counseling, and other management.

Font Size:
A
A
A
Background:
Blank
Blank
Blank
Blank Blank

Switch from Effexor back to Paxil without tapering?

I've been trying Effexor for about 3 months now and I've decided it's NOT working right for me.  I'm up to 225mg.  I want to go back to the med combination that I was on before, it was working MUCH better for me, it was 20mg of Paxil plus 150mg of Welbutrin.  I'm completely miserable and want to make the switch as quickly as possible.  I'm wondering if anyone knows if it is safe/ ok/ reccommended to change without tapering one and slowly increasing the other?  I'm going to do this under my doctor's supervision but would like to hear if anyone has any experience with this as I don't fully trust my dr.
Related Discussions
4 Comments Post a Comment
Blank
Avatar_m_tn
in the case of Effexor (Venlafaxine) it is ok to start most SSRI meds (Including Paxil) without first tapering down on the Effexor. In fact many people take Effexor along with an SSRI med as part of their treatment.

Effexor is different enough from Paxil that the odds of an adverse interaction is very uncommon. Now you would not be able to do the same with another SSRI like Zoloft, Lexapro, Prozac, ect. Simply because these and Paxil are SSRI medications and you would risk developing Serotonin Syndrome from that combination.

Effexor is an SNRI and works much different than SSRI's. Thus no fear of interaction.

It still may not be a bad Idea to at least taper down to about 75 Mgs of Effexor before ramping up the Paxil and Welbuterin. Then after the Paxil and Welbuterine start to work then back down to 37.5 on the Effexor, then off it completly.

Given that you are going to put Paxil and Welbutrine in place of the Effexor, your withdrawl (withdrawal) from the Effexor should be much more tolerable then say, someone just stopping Effexor and not replacing it with another AD medication.

Of course ask you Doctor, but this is the way my Psychiatrist explained it to me when at one time I added Effexor to my Zoloft.

I forgot to mention that Welbuterin is also safe to take with both Effexor and Paxil. Welbuterine only effects the reuptake of Dopamine which the other two do not, thus no fear of interaction.

Either way I still think it better to taper a bit on the old med before introducing the new one.
Blank
Avatar_f_tn
Hi,

I was on effexor when I decided to try paxil, and I took both at the same time
without any problems.  My pdoc approved and eventually I did come off the
effexor but I stayed on both for several months without any side effects.

Best wishes,
starr28
Blank
Avatar_m_tn
Hello. I don't know much, so this may be a really dumb question. May I ask why you wanted to change from the things that were working for you in the first place?
Blank
Avatar_f_tn
DO NOT go cold turkey with the Effexor , especially with the high dose you're on .  Effexor is a 'dependent ' medication , meaning you have to slowly wean yourself off of it gradually , otherwise you'll experience horrible headaches , vomiting , and dizziness  - not fun !    I've been on it for several years and if I forget to take mine at the regular time I start to get a headache and then I quickly remember .   The dr. will most likely give you drug samples to wean you off in lower doses .  I hope this helps :)
Blank
Post a Comment
To
Recent Activity
1174869_tn?1333665348
Blank
Mood Tracker: August 21, 2015
1 hr ago by char1234vass
1174869_tn?1333665348
Blank
Mood Tracker: August 21, 2015
1 hr ago by char1234vass
1174869_tn?1333665348
Blank
Mood Tracker: August 21, 2015
1 hr ago by char1234vass
Blank
Mood Tracker
Track your mood over time
Start Tracking Now
Top Mood Disorders Answerers
1110049_tn?1409405744
Blank
4Maddie44
Dorset, United Kingdom
1551327_tn?1414146344
Blank
Bubulous
Tompkinsville, KY
Avatar_f_tn
Blank
Crystal413
VA
Avatar_f_tn
Blank
ggreg
NC
1257808_tn?1322765815
Blank
MR_WHY
Other
Avatar_f_tn
Blank
JE55LEW
MANCHESTER, United Kingdom
Depression Community Resources
RSS Expert Activity
233488_tn?1310696703
Blank
Marathon Running Done Over Many Yea...
May 21 by John C Hagan III, MD, FACS, FAAOBlank
233488_tn?1310696703
Blank
New Article on Multifocal IOL vs &q...
May 21 by John C Hagan III, MD, FACS, FAAOBlank
748543_tn?1371753642
Blank
TMJ/TMJ The Connection Between Teet...
Jan 27 by Hamidreza Nassery , DMD, FICOI, FAGDBlank
Top Mood Disorders Answerers
1110049_tn?1409405744
Blank
4Maddie44
Dorset, United Kingdom
1551327_tn?1414146344
Blank
Bubulous
Tompkinsville, KY
Avatar_f_tn
Blank
Crystal413
VA
Avatar_f_tn
Blank
ggreg
NC
1257808_tn?1322765815
Blank
MR_WHY
Other
Avatar_f_tn
Blank
JE55LEW
MANCHESTER, United Kingdom