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Wellbutrin/bupropion and decongestants
A few years ago I was on Wellbutrin for a while... Along with other meds, including Alavert, a decongestant/antihistamine.  I stopped taking the Wellbutrin against my doctors wishes, because I felt it was making me aggitated.
Now I am back on Wellbutrin. Actually Bupropion SR (generic)  I read the info sheet that came with it and noticed a new warning... do not take decongestants with this medication.  That warning was not on there before when I took it.
Does anyone know what the interaction is?
I am wondering now, if taking Alavert with the wellbutrin is what was making me so aggitated? Does anyone have any info on this, or personal experience?
thanks
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962875 tn?1314213636
Wellbutrin and decongestants  are both stimulants (which would explain the agitation) and can both increase blood pressure, so the two meds together could bring on a hypertensive crisis (esp. in someone who already has high blood pressure), and this could even lead to a  stroke.

Ask your pharmacist about the safety of taking any particular decongestant along with your Wellbutrin. An antihistamine alone (not combined with a decongestant) shouldn't be a problem, but again, check with the pharmacist to be sure.

Best wishes...
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