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anyone taking Prestiq

I was diagnosed with Chronic Major Depression, Anxiety dis-order and ADD W/O hyperactivity since taking Chemo nearly 4 years ago.  I am considered drug resistant so now they have taken me off of Celexa and put me on 100mg of Prestiq and Xanax 1 mg 2x a day and 2 at bedtime.  I cannot go outdoors or do the simple things.  I am always frightened to try yet another drug.  They wanted to do a shunt thing and I said no way.  How is Prestiq?  thanks
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Avatar universal
I also have been taking Pristiq. Been about 5 months now at 100Mgs a day.
I'm not so keen on this Pristiq. Like Morningside, I just never really got any measurable anti-depressant effect from it.

My Pdoc added Lithium and Lamictal to the Pristiq and that is helping a little, but I'm still not sold on this Pristiq. In the past I did better on Effexor and other AD's like Lexapro. (unfortunatly they stopped working for me so I was switched to Pristiq)

I seem to build this damn resistance to antidepressants if I take them for long periods. That's why all the med changes. It really pisses me off too.
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Avatar universal
I find this is typical.  I am drug resistant; so the Psychiatrist says.  He even wanted to put some kind of shunt in my carotoid artery to the brain that gives a tiny shock...have you heard of this?  My problem is I had to take Interferon which made me depressed and physically ill with pain.  After I finished the Tx and the side effects didn't go away I was told I am depressed.  Of course I'm depressed, I don't feel well!  My Psychologist said it was caused from the Interferon-my shrink can't find a medicine that helps and like you the Prestiq has done absolutely NOTHIING!  Oddly I can take Hydrocodeine and I feel good-of course that is addictive. Sorry you lost your dad.  Good luck to you too, Frank
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Avatar universal
I am 51 year old female who was put on Pristiq about 3 months ago.
It did nothing for my depression and so they upped it to 100mg
and still nothing. Then they added 300mg Wellbutrin and that
didn't help. I am still on the Pristiq but now Doc added abilify
to the P and W and that didn't help. So now I am still on the
Prestiq and Wellbutrin and added Zyprexa. I have been on
these meds for 10 days and still feel that over all the Prestiq
never helped me. I never even had 1 side effect from taking the
Presitiq--like I was taking nothing. I want to get off the Prestiq
and try to get back on the Lexapro that pooped out on me in
December while I was under some stress for a death in my family.
Sorry I didn't have anything to tell  you but my doc did tell me
finally that if 50mg  of the Pristiq didn't work for you that the 100mg
will not either. Now he tells me! I guess that means Effexor
wouldn't work on me either.  Who knows what is next.
Good luck.
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