been on antidepressants for years-smoked marijuana last night
im on ativan-0.5mg,procyclidine-2.5mg,zyprexa-5mg and paxil 10 mg for the last 5,6 years...i am 21,male...last night i smoked some marijuana for the second time in my life....its been 24 hours since i smoked....i need to take my medicines again...i got sober after 3 hours of smoking....its been almost 38 hours since i last took my medicine,i really need to take them again....what do i do?
i can't from my one time experience...my heart was beating at 105-110 beats per minute for 3 hours,my mouth and lips were dry,i had to drink about 10 bottles of water,i thought i'd die...but things calmed down after 3 hours...i don't think ill ever do it again,maybe i was smoking some really hard stuff for the first time in my life....my friend said it happens to everybody in the start,i can drink with no side effects but these three hours were the worst in my life....
What happened is caused by a decreased GABA (chief inhibitory neurotransmitter) induced by activation of the CB1 receptor due to the psychoactive substance THC you get by smoking or ingesting cannabis.
Low levels of GABA can be linked with anxiety with high levels have a relaxing effect. You mention you take Ativan, this is a benzodiazepine. Like most benzodiazepine, Ativan will work by increasing the level of GABA by affecting the GABAa receptor. This cause a the relaxing, hypnotic and sedative effects of benzodiazepines.
Chronic exposure to benzodiazepines will result into severe withdrawal symptoms if you don't take them as directed. The withdrawal symptoms are usually anxiety, muscle spasms, irritability and in rare case seizures. In no way you should stop taking the Ativan, it have a short half-life of about 10 hours so the withdrawal symptoms can appear really fast. By smoking weed you produced a decrease of GABA therefore producing anxiety symptoms like increased HR and probably high blood pressure. The way to counter this would have been to take the Ativan and cannabis at the same time.
You don't have to worry about the rest and please take your medications, there are no interactions apart from what I said above. The interaction I said is called a increase/decrease interaction.
What I say is that you should not skip doses. I don't say you won't have a panic attack if you smoke when combined with the Ativan but the chances are less likely. THC is a drug like any other drug, some can't handle it while some others can. One drug does not fit all.
Weed gives me panic attacks really bad.
But it doesn't really have any interactions with any of your meds except ativan.
If you DO decide to smoke, don't change your regular course of prescribed meds
the weed might make the ativan a little less effective but skipping a dose reduces its efficacy to zero. I reccomend not smoking, I used to do it all the time then it started giving me panic attacks. Now I stick to prescribed meds.
its been like 4 days and despite taking my regular medicines im still panicky and anxious all the time,i was feeling so great before smoking marijuana...its like all my fears have come back again for whom ive taking the medicines over these years,im not really depressed but very nervous and anxious,i get scared very quickly and i panic very easily too...i want to get back to normal..please advice,my university is starting soon,i won't be able to study like this:(
The marijuana didn't do any long term damage. You've learned your lesson not to smoke it and after a couple days you should be feeling back to normal. I think at this point it might just be that you are anxious about falling back into anxiety. In my experience if I overthink my level of happiness I am doomed to be unhappy, but if I just immerse myself in daily activities and friends and such I will forget all about it and move on with things.
It sounds like you have yourself convinced that the weed got you all messed up and anxious. I would try to avoid comparing how you felt before and after smoking weed, because if you obsess about it, it will be easy to convince yourself that you feel bad. Just be confident that the weed didn't do anything to your physical, emotional, or mental health in the long term and that you'll be fine in a week or so by the time university starts.
Just my advice, but I had a similar experience when I started to have anxiety. I smoked weed and had a panic attack and was afraid I would never be the same again. Well I'm back to normal and the only thing worrying about the weed did was exacerbate the anxiety that was the problem in the first place.
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