cymbalta and zyvox

Do not take these two meds together.

[M4Y0U]

True. Potentially serious pharmacodynamic interaction. Never use this combination.

[MMahon]

http://en.wikipedia.org/wiki/Linezolid#Adverse_effects

Interactions
Linezolid is a weak monoamine oxidase inhibitor (MAOI), and should not be used concomitantly with other MAOIs, large amounts of tyramine-rich foods (such as pork, aged cheeses, alcoholic beverages, or smoked and pickled foods), or serotonergic drugs. There have been postmarketing reports of serotonin syndrome when linezolid was given with or soon after the discontinuation of serotonergic drugs, particularly selective serotonin reuptake inhibitors such as paroxetine and sertraline.[9][110][111][112] It may also enhance the blood pressure-increasing effects of sympathomimetic drugs such as pseudoephedrine or phenylpropanolamine.[5][113]

[M4Y0U]

I don't understand why MAOI are still being prescribed anyway... So many interactions and serious ones....

[MMahon]

I took an MAOI for over 20 years with no problems.  It was the best anti-d for me and I tried a lot of them over the years.   I was careful over possible interactions but never ran into conflicts.   If you can improve with the current anti-d's then your better off but if you can't it's well worth the try.  After all most of the many new anti-d's out there don't do anything much different then these do.