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duloxetine withdrawal

Is there any way to alleviate the symptoms of duloxetine withdrawal? How long do symptoms usually last, and will they go away on their own?
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First thing to note, if your still experiencing withdrawals after 28 days, it may mean you need to go onto a small dose of the drug again, Unfortunately smoking does affects the amount of duloxetine in your system and blood stream meaning that you will loose between 40 - 50% of the duloxetine dose you take. It is not uncommon for people to have their duloxetine prescription increased if they smoke. Unfortunately it is not uncommon if you miss a dose to be experiencing these problems if your on a high dose, my patients even at a dose of 30mg do experience brain zaps, nausea and vomiting even with just one day missed. This is why duloxetine should be withdrawn extremely slowly and only under professional help. I always recommend being on duloxetine for a solid 12 months at the right dose for you before you even consider reducing or think about coming off the drug, kind regards
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Always good to have someone new on here, but just to let you know, this post is 9 years old -- one hopes the poster is fine by now!
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Every body is different, I recommend if your still experiencing problems after 28 days, to at least go back onto a small dose of duloxetine
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Avatar universal
First thing to note, Unfortunately smoking does affects the amount of duloxetine in your system and blood stream meaning that you will loose between 40 - 50% of the duloxetine dose you take. It is not uncommon for people to have their duloxetine prescription increased if they smoke. Unfortunately it is not uncommon if you miss a dose to be experiencing these problems if your on a high dose, my patients even at a dose of 30mg do experience brain zaps, nausea and vomiting even with just one day missed. This is why duloxetine should be withdrawn extremely slowly and only under professional help. I always recommend being on duloxetine for a solid 12 months at the right dose for you before you even consider reducing or think about coming off the drug, kind regards
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Avatar universal
Thanks. :)
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You should feel better in a couple weeks. Sometimes it can take three to four weeks depending on what you dosage was.
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No, I'm not taking anything else. To be honest, I really don't want to go back on medication at all. I'm just hoping that I can start to feel normal again soon.
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Could be a few weeks before your withdrawl symptoms fade.

Are you swapping it for a different AD medication?
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