extreme exercise-zoloft effects gone

Taking 100 mg opf zoloft and then the next morning riding 20 miles the next day it seems as thoiugh the positive of zoloft are not there. I am weary

[Hensley258]

I suppose it is possible that the increase in exersise could be speeding up your metabolism, such that your body is breaking down the medication faster.

I'm not saying I have ever heard that this is possible, but you never know.

You may want to talk to your doctor about going up to 150mgs a day.
If I recall correctly, I think 250mgs a day is the maximum effective dosage for Zoloft.
I know most people taking Zoloft, take between 100 and 200Mgs a day.