My experience with mirtazapine is and was a good one I guess (currently tapering it).
First thing mirtazapine did was making me extremely sleepy when I started it at 15mg, took it before bedtime and it was knocking me to bed. I noticed more intense vivid dreams during my sleep. Mirtazapine does not suppress the REM sleep.
Then I upped to 30mg after 1 week, it was still knocking me down, I liked that fact since I tend to suffer from insomnia. But the hypersomnia was getting worse, can sleep 12 hours without any problems on it...
I noticed an increased appetite but no weight gain for me since I have an extremely fast metabolism. But it could be a problem for someone older or already with a BMI above the average.
-No nasty side-effects when I started it
I consider mirtazapine an extremely good antidepressant with few side-effects. I'm having no problem stopping it, can skip many days without it with no withdrawal effects. It's a unique antidepressant in it's kind (tetracyclic) and it will work by antagonizing the 5-HT receptors rather than inhibiting the reuptake of serotonin like the SSRIs.
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