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As for stomach upset it depends on the cause. With some medications that cause this taking food or milkBreast milk Breast milk jaundice Lactose intolerance Nipple discharge - abnormal with them can be helpful. Also sometimes there is an extended release or coated form. It depends on the medication. As regarding nausea I could not tolerate lithium (as an example) but the coated/extended release brand Lithobid was fine. Ask your psychiatrist about options. The same as regards effect on sex drive which varies. "Depression Central" is a good website that has information you could discuss with your psychiatrist.