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Yes, smoking most definitly causes more anxiety if you are prone to that disorder which usually goes hand in hand with depression. I stopped smoking 7wks ago and began with the losenge, but couldn't tolerate the side effects so stopped after 5 days and just went cold turkey. Your still ingesting nicotine so eventually would have to go through w/d from the losenge too so I figured just get it over with. The anxiety attacks, constipation, sinus problems lasted 3wks straight, but after that every day got a little better. I used Xanax to get me through the anxiety attacks. I felt like I was going to have a seizure, my heart would pound so hard and I would start to panic. Xanax helped alot. I noticed my lungs felt better almost the first day and the change in the appearence of my skin tone and energy level is an unexpected surprise. After 5wks I started to feel all wound up and still unable to sleep(forgot to mention 3wks of insomnia, but that will get better if you sleep well in the first place) I am an insomniac and have been since 17years. I now remember why I started to smoke in the first place. My point is if you began smoking to manage stress in the first place, that problem will still exist as I am finding out. Excercise and diet are key to stress management as smoking is only a quick fix. Finding out why you are stressed or depressed is the first step to being a successful non-smoker. This was not hard for me because after so many years I came to HATE smoking, but dealing with stress without my usual outlet is really difficult. I don't want to "smoke" per say, but I do crave some relief from this manic feeling. Please remember though that the physical withdrawals do not last forever even it may feel like it at the time. GOOD LUCK!