Blood Work

Hello,  I got my blood test back.   My WBC count is 8.5 ( 4.3 to 10.0) falls in the normal area.

My concerns are  

Mean Platelet Volume 11.0 , should be (6.9-10.9) which is flagged high.
Segmented Neutrophils 74.0  (42.-71.0)  high.
Lymphocytes 17.2 (24.0-44.0) LOW.  {Oct. they were 22.0 and Sept. 32}
Monocytes 8.0 (2.0-12.0) normal.   {Oct. they were 9.2 and Sept. 10.0}
Eosinophils .5 (0,0-8.0) normal.  {Oct. they were 1.3 and Sept.  2.0}
Basophils .3 (0.0-2.0) normal.  {Oct. they were .3 and Sept.  1.0}

RBC count was 4.93 which normal.  Everything else was normal.

T4 (Thyroxine, Total 7.6 (4.5-12.0) normal.

Urine  all normal even glucose, fasting 76 (65.99)

Except for LDH, Total 237 (100-220) high.

My concern is the Lymphocytes because in Oct. they were 22.0 (24.0-44.0) and in Sept. 32.0 they were 32.0(24.0-44.0 now. They are 17.2(24.0-44.0).  

So, I can have HIV or AIDS because the Lymphocytes are going down.

The doctor stated that if Neutrophils are high that Lymphocytes go down.  

Why do I have a normal WBC count if the Lymphocytes are going down compare to other times which the WBC counts were lower Like Oct.  6.8 and Sept  5.6?  

I acquired the infection what I have in mid July, I figure the WBC would be low like this, but my Lymphocytes go to up not down.  

The Doctor stated they look at the WBC count not the individual parts.

Have another question I noticed every time I take Amoxicillin / Clavulanate Potassium 500mg I get a thigh rash.  Last time was in November after finishing it, I noticed my thigh turn red a little and after a week it was very rashly.  I Then went to the Doctor.    For information, I was given three times in the last 5 1/2 months this medication.  I barely thought about now.

I tested positive for HHV 6 Herpes could that of cause some of the issues?  I heard that  herpes disease is very bad, or it is reactive, which would still be bad.

Thank you for taking your time for me.

[Jasmina Jankicevic, MD, MSc, CCRP]

We understand your efforts to solve all diagnostic dilemmas around your condition. Our answers (within the scope of this forum) are below:

1. Person is HIV positive only if specific blood tests (especially ELISA and Western Blot) are positive after a window of several weeks to several months. So far, you tests were negative, and it is not beneficial for you to build anxiety. Your final conformation will be that 6 month ELISA and Western Blot (if required) test. Your blood work results are inconclusive without further investigation of your physician whether you have or not any chronic condition (such as autoimmune disease, infection, etc.).

Just for your information, AIDS is established as diagnosis when certain signs or symptoms defined by the U.S. Centers for Disease Control and Prevention (CDC) are present, including less than 200 CD4+ T cells per cubic millimeter of blood (compared with about 1,000 CD4+ T cells for healthy people), and CD4+ T cells accounting for less than 14 percent of all lymphocytes. So, if necessary, your lymphocytes will be looked into more specifically with additional tests. It would be best to discuss that with the infectious disease specialist.

2. Rash appearing every time at the same location after taking the same drug is known as Erythema fixum, and requires suspected drug to be discontinued and short-term treatment for lesions is usually recommended. However, as you know, differential diagnoses always exist, and medical history plus lesions should be evaluated by a physician before final diagnosis is established.

3. The Human Herpes Virus 6 is the cause of Roseola, mostly benign disease (high fever lasting for 3-5 days, runny nose, irritability, tiredness, and subsequent rash on face and body)  characteristic for childhood (age of 6 months till 3 years), rarely seen in adults, and it provides lifelong immunity. Recent studies are indicating possible connection of HHV 6 with some neurological disorders but that is really not in the scope of the Dermatology Expert Forum.

Wishing You Optimal Health,
Dr. Jasmina Jankicevic