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I have AN

by aperitis, Feb 18, 2009 11:22PM
I am a 27 year old male.  I have had Acanthosis Nigricans, (self diagnosed) for as long as I can remember.  It is in my armpits and in my groin and it is absolutely unsightly.  I have been overweight most of my life but have started to lose weight.  At my heaviest I was 311.  I am now down to around 280 and hoping to lose 100 more pounds.  

I understand that AN is tied to obesity.  I have looked all over the web for a straight answer.  I just want to know once and for all.  If I lose weight, will this unsightly brown leathery skin go away?  Will creams work or are they a scam?  Will laser ablation work?  If all else fails can i have that part of my skin removed?  I just want it gone in the worst way.
Member Comments (5)

by aperitis, Feb 19, 2009 01:24PM
anyone?   please

by aperitis, Feb 21, 2009 01:59PM
I know it is annoying to keep bumping the post, but I really need an answer on this.  Please...anyone, anyone at all with knowledge of this condition.  Please help me on this.  This skin thing is killing my self esteem.

by Rowena Santos, MD, Feb 21, 2009 02:25PM
Hi,

Diagnosis of acanthosis nigricans is by clinical examination and some  tests such as skin biopsy, blood tests, endoscopy and x-rays to rule out diabetes or cancer as the cause.   Correcting the underlying cause results in resolution of the lesions. If this is obesity associated AN, losing weight is important.  Treatments considered are used primarily to improve cosmetic appearance and include topical retinoids, dermabrasion and laser therapy. This link may help: http://emedicine.medscape.com/article/1102488-treatment

Take care and regards.

by aperitis, Feb 21, 2009 02:34PM
I am already using South Beach Skin Solutions lightening gel for sensitive areas.  I'm 2 days into it and supposed to see results in about 2 weeks.  But my mom got me a tube of hydroquinone stuff so I'll try that too.  

But my question is:  If/When I get to my goal weight, will the dark skin be completely gone or will it still be kind of visible?

by Rowena Santos, MD, Feb 21, 2009 02:46PM
Hi,

Acanthosis nigricans often fades if the underlying cause is known and treated appropriately. I would still recommend that you have this evaluated by your doctor for proper management. The application of your present  medications may be futile if the underlying cause is not known.
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