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Dermatology  (Expert Forum)
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Need Help... Is this a reaction to antibiotic?
Answered by
Alan Rockoff, MD - dermatology, Child Skin Problems
The Rockoff Dermatology Center Brookline - MA
Welcome to the DERMATOLOGY FORUM! Questions in this forum are answered by Dermatologists from St. Luke's Roosevelt Hospital, under the direction of Andrew Alexis, M.D., M.P.H.

Need Help... Is this a reaction to antibiotic?

by biggestfool, May 03, 2006 12:00AM
I have attached a couple of pictures of the rash in question.  Here is my background:

4/3 - started 10 day course of minocyclin
4/13 - finished antibiotics
4/19-4/20 - began breaking out with rash on legs

The rash is composed of many tiny red dots, not much bigger than the tip of a pen.

Also, the rash has stayed on my legs and is located primarily below my mid thighs.  The rash does itch, but not unbearably so.  It seems to be worse (redder, itchier) after working all day, and seems to be faded and less noticeable when I first get up in the morning.

I have been alternating between hydricortisone and benadryl to control the itching.  The rash has persisted for almost 2 weeks without clear signs of getting better.

I am not 100% sure this is related to the minocyclin, but I can think of no other changes to my environment that would cause this.

Please advise what this may be.  I am worried that this is a prolonged, serious reaction to the antibiotic.  Thank you!

http://temporary23.myphotoalbum.com/view_album.php?set_albumName=album01

by Alan Rockoff, MD, May 05, 2006 12:00AM
These dots look like broken capillaries.  A drug reaction is possible, though far from certain, especially since the spots don't sound like they're going away.  There is an unimportant condition called Schamberg's Disease, in which capillaries cause small, red-brown dots, always on the lower legs.  In younger people, it usually goes way on its own--no treatment is available.

Ask a skin doctor to have a look, if the spots persist.

Best.

Dr. Rockoff
Member Comments (3)

by Demiguise, May 08, 2006 12:00AM
I didn't look at site but you can get this type rash from BP+
diuretic (sulfa) meds. It 'accumulates in system & then occurs.
Another is an 'acquired reaction' to soaps/softeners since it's
over the same part on both legs. Maybe up/dwn friction. If it
goes to shins, it's probably a vascular condition from a med. I
got tiny red-dots & then to dull purple rash after I was put on
bp+hct rx. Took 6 mo. before started. Sulfa is really sulfonamide & not like they use in foods.

by biggestfool, May 10, 2006 12:00AM
To: Demiguise
It did move to the shins.  Ended up spreading up and down both legs, front and back.  It has been about 3 weeks since it started, but I would say it is about 80% gone now.

From most of what I have read and pictures I have looked at, it seemed to be either vasculitis or Schambers.  From what I have read, these are possible reactions to the antibiotic.  I haven't seen my Dr. yet, but my only concern at this point is whether the reaction caused any permanent damage - i.e. can I expect to deal with this for life now.

I'm going to have to be dying before I take any more antibiotics.  I have only taken 3 in my life and have had reactions to all 3 of them.  The cons of many of these medicines almost outweigh the benefits.
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