This may be a condition known as FOCAL PALMAR PEELING or
Exfoliative keratolysis (Keratolysis Exvoliativa) or Acral Peeling Skin Syndrome. Read up on these conditions as there is a lot of info on the internet that may interest you. Several members of my family have had this condition at various times. Usually it comes unexpectedly and goes away on its own.
My brother suffered with this for 40 years, seeing many Dermatologists who alternately diagnosed eczema, psoriasis, etc. Their treatments consisted of cortisone creams or antibiotics. They were ineffective, ultimately. Finally, he switched med plans and went to a new Dermatologist who suggested a biopsy. Nothing turned up but “super dry skin”. She said it may be caused by an auto-immune response to some trigger or exposure to something. She gave him a sample of a hand cream with a high level of Urea. This immediately caused a reduction in pain, redness, cracking etc. Multiple daily applications later, and it was gone! Whenever a flare-up occurs, he applies this cream and it stops it dead. Some of these higher level Urea creams can be ordered online and others need a prescription.
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