Normal Immune Normal Tests except Skin

Hi Dr, hope you can help

I am a 44 year old male, single relatively in good health and do try to eat right. Some lower back(disk), joint problems(knees), the occasional headache, acid reflux and not overweight. I have had a lot of skin problems though since i was 17. Namely cystic acne for which I am currently taking a 3rd lifetimes worth of Accutane. I am currently in my 5th month of treatment. Have dry eyes(using eye drops) and lips(blistek). I was one of the first patients in 1982 to take this drug before the FDA had approved it. Because of this thankfull wonder drug, my scarring throughout the years has been minimal, most scarring is to my back.

My monthly blood tests have come back normal except the elevated level of Cholesterol. STD's have been negative except for HSV 1&2 and what my doctor and I think is mulloscum contagiosum(mostly on penis).
I have never had a HSV2 breakout anywhere but prop was exposed during my life. HSV1 and mulloscum on the penis are so similar that I cant really tell them apart when it comes to the proper home treatment. For HSV1, I use Valtrex, which works well. Mulloscum (if thats what is really is) seems is more difficult to treat. My conditions: Acne, HSV1, Mulloscum are very similar in nature as they all have a white core when forming under the skin. This recent treatment of Accutane has been pulling things out of my skin that I never imagined where in there(really disgusting) including a stye in my left eye.

I recently developed a 'breakout' on the shaft of my penis which always start out very small and then gets out of control. I took my Valtrex for 2 weeks.....still there. Then I tried my OTC products Acne med including salicylic acid, tee tree oil, hydocortisone, silver, vinegar, Neosporin......still there. Then I went and got Dr Scholls Feeze off wart remover(this does work for mulloscum). Lightly froze it and let it heal for 2 weeks. The skin around it didnt heal properly. I squeezed it and some of the white curly curd came out, the sac was prob very deep and big.(i had this a year ago in the same location on the penis, figure didnt get it all).

To get it all, I re-froze it but over did it and now have an infection that looks like a form of Lichen Simplex(also looks likes a Syphilis chancre). A hard white skin like callous center surrounded by red inflamation (inflammation) about the size of a nickel. I went to urgent care after this condition got worse. I am on a 10 day oral antiboitic(keflex) and topical antiboitic(bactroban). My 6th day is Monday, 5-4, There has been some improvement so far but not really healing. Still some burning and itching and when I pull the band aid off to replace, still seems to bleed a little bit. I did pull out what looked like a cutaneous horn after the bactroban started working slightly removing the callous. Under magnifcation, the removed skin has a scratchy appearance, but the 'horn' just maybe skin or dried blood.


How much of these skin issues are hereditary and have a pre-disposition for infection?
All of my family has skin issues, Acne, boils, moles, cold sores...etc
I have been doing a lot of internet research on skin disorders to see whats really wrong with my skin or me.

My next Accutane apt is Friday, what should my doctor and I look for if the antibotics didnt work?
salicylic acid poisoning?
Lichen simplex?
an autoimmune disorder?
Gram-negative?
A yeast infection?
a form of Skin cancer?
Allergies?
Dermatitis / Folliculitis?

Please help....
KC