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My 23 month old son was diagnosed with a solitary mastocytoma on this arm. He has recently been breaking out in hives and whelps and the skin gets blotchy in places and it goes an comes. At times they get worse then others. One doctor seemed to think that the mastocytoma was producing histamine into his body and causing him to break out . Another said the the hives and whelps have nothing to do with it an that it is a virus. I have him on zyrtecZyrtec Zyrtec dye-free sugar-free Zyrtec hives Zyrtec-dtwiceTwice-a-day a day and he is still breaking out. Is this normalNormal saline flush and can a mastocytoma cause this? He has a long history of suppressed immune system. Last December he had KawasakiKawasaki disease disease. Any answers would be helpful.