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Dermatology  (Expert Forum)
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Wanting another opinion on results
Answered by
Alan Rockoff, MD - dermatology, Child Skin Problems
The Rockoff Dermatology Center Brookline - MA
Welcome to the DERMATOLOGY FORUM! Questions in this forum are answered by Dermatologists from St. Luke's Roosevelt Hospital, under the direction of Andrew Alexis, M.D., M.P.H.

Wanting another opinion on results

by uagrad, Sep 06, 2007 12:02PM
Hey, just wanting another opinion about biopsy results off of several moles i've had taken off recently.
-3 of these - A compound melanocytic proliferation is present in these sections. The junctional component has both a nested and non-nested pattern with fusion of rete ridges, papillary dermal fibroplasia, and patchy lymphocytic infiltrates. The junctional melanocytic component is characterized by mild to moderate cytologic and architectural atypia and extends laterally away from the more central dermal component. Nest of superficial dermal nevomelanocytes are present.
-2 of these - A compound melanocytic proliferation is present in these sections. The junctional component has both a nested and non-nested pattern with fusion of rete ridges, papillary dermal fibroplasia, and patchy lymphocytic infiltrates. The junctional melanocytic component is characterized by mild cytologic and architectural atypia and extends laterally away from the more central dermal component. Nest of superficial dermal nevomelanocytes are present.
-1 of these - Sections through this tangetial specimen show a relatively small, but poorly circumscribed lentiginous junctional melanocytic proliferation. There is focal nesting with mlanocytes predominantly arranged as single cells extending in a somewhat crowded manner along the dermal-epidermal junction. Assoctiated lentiginous epidermal hyperplasia is present. there is patchy lymphocytic inflammation present in a perivascular distribution. The melanocytic proliferation approaches, but does not technically appear to involve the sampled microscopic edges.

One of the mild-moderates had positive edges on the biopsy so she went back in and cut out a lot more, big scar, and it came back clean. Just wondering what you think, my dermatologist isn't too worried about anything and just wants to see me every six months unless i notice any changes.  thanks for your opinion. Im a 25yr old male if that matters.

by Alan Rockoff, MD, Sep 06, 2007 09:37PM
To: uagrad
I agree with your dermatologist.  These pathologic changes do not sound worrisome.  In general, it's not that helpful to try to interpret your own lab tests, including pathology reports.  If you have questions about them, you're best off discussing them with the doctor who ordered the tests.

Best.

Dr. Rockoff
Member Comments (1)

by Setter2, Mar 10, 2008 05:58PM
A related discussion, re-excision question was started.
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