's foot can be treated at home using an antifungal medicine to slow the growth of fungi. Topical nonprescription antifungals usually are used first. These include terbinafine (Lamisil AT), miconazole (Micatin), clotrimazole (Lotrimin AF), and tolnaftate (Tinactin, Tinaderm). Prescription antifungals may be tried if nonprescription medicines are not successful or if you have a severe infection.
Desonide Cream is a topical corticosteroid. It works by reducing skin inflammation by stopping the production of certain chemicals in the body. This is not used for athlete's foot.