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Dermatology (Expert Forum)
safety
Answered by
Alan Rockoff, MD - dermatology, Child Skin Problems
The Rockoff Dermatology Center
Brookline - MA
Welcome to the DERMATOLOGY FORUM! Questions in this forum are answered by Dermatologists from St. Luke's Roosevelt Hospital, under the direction of Andrew Alexis, M.D., M.P.H.
safety
by Sharon, Jan 23, 2000 12:00AM
I am doing a research study to determine if the test article is absorbed into the bloodstream when applied once daily for 8 weeks to the forearm. The test articles are a combination of TRETINOIN ( a drug derived from vitamin A used for acne), HYDROQUINONE (a drug used for bleaching the skin), and FLUOCINOLONE ACETONIDE(a steroid drug used to reduce inflammation) in a cream base. This formulation is used to lighten the skin when hyperpigmentation is present. 1 gram/day for eight (8) weeks. I need to know if these test articles are absorbed into the blood stream if their could be ANY danger to my health or skin???
Doctor's Answer
by Alan Rockoff, MD, Jan 23, 2000 12:00AM
, Jan 23, 2000 12:00AM
Sharon:
You are describing he so-called "Kligman formula," devleoped in the 1970's by the eminent Philadelphia dermatologist, Dr. Albert Kligman. Each ingredient is itself in wide use. Why are you researching the safety of things used safely for so long? (Use in pregnancy is another matter, when greater caution is exercised.)
best.
Dr. R
You are describing he so-called "Kligman formula," devleoped in the 1970's by the eminent Philadelphia dermatologist, Dr. Albert Kligman. Each ingredient is itself in wide use. Why are you researching the safety of things used safely for so long? (Use in pregnancy is another matter, when greater caution is exercised.)
best.
Dr. R
Member Comments (3)
by steve, Feb 19, 2000 12:00AM
i tried that combination in the 70's to eliminate a cafe au lait spot.....it doesn't work at all. try a laser.
by Interested Party, Mar 17, 2000 12:00AM
to you ,very wise to study,drugs used for long time do not make them safe!to doctor who answered,are you kidding!drugs,as you well know,have many adverse reactions,i would assume the truth,may affect your kickbacks from the pharmacuetical company.who can shame you for watching your wallet!
