unknown large vaginal ulcers since age 11

I'm a female age 23, and since the age of 11 I have had large and extremely painful vaginal ulcers.  They are almost always one at a time ranging in size from a pencil eraser to larger than a quarter.  I have been through a few biopsies and dozens of blood tests.  Herpes, std, chrons, bechets, and hiv have all been ruled out NUMEROUS times.  I have gone through oral and topical steroids, valcyclovirs, etc.  As it has been over a decade I am begining to lose hope.  I get one almost every couple months with no precurser or reason. I have monitored around my menstral cycle, foods, stress....nothing is consistant. PLEASE HELP ME!

[Bhupinder Kaur, MD]

Hello,
I can understand your agony for your symptoms. Some of the other possibilities(apart from the ones that have been investigated) are chancroid, lichen planus, lymphogranuloma venereum, syphilis, Reiter’s syndrome and Stevens Johnson syndrome. My sincere advice would be to consult these possibilities with a venereal and sexually transmitted diseases expert. It is very difficult to confirm a diagnosis without examination and investigations.
I hope it helps. Take care and please do keep me posted on how you are doing. Kind regards.