vitiligo and narrowband UVB

How effective in narrowband UVB + tacrolimus oint is this regimen better than PUVA sol or PUVA?
Thanks
Ray


This discussion is related to treatement for vitligo.

[BhumikaMD]

Hi,

'Topical tacrolimus ointment (0.03% or 0.1%) is an effective alternative therapy for vitiligo, particularly when the disease involves the head and neck. Combination treatment with topical tacrolimus 0.1% plus the 308-nm Excimer laser is superior to monotherapy with the 308-nm Excimer laser monotherapy for UV-resistant vitiliginous lesions.

The combination of topical calcipotriene and narrowband UV-B or PUVA results in improvement appreciably better than achieve with monotherapy.

PUVA treatment (8-methoxypsoralen, 5-methoxypsoralen, trimethylpsoralen plus UVA) was often the most practical choice for treatment, especially in widespread vitiligo . However, 2 or 3 treatments per week for many months are required before repigmentation from perifollicular openings merges to produce confluent repigmentation.'

You could read more about this at the following link -

http://www.emedicine.com/DERM/topic453.htm

Let us know if you need any other information.

Regards.