-lowering agents such as statins, fibrates, bile acid–binding resins, probucol, or nicotinic acid. The lipid-lowering effects of these agents have been well documented, but few studies mention the efficacy of these drugs for resolving xanthomas.
Eruptive xanthomas usually resolve within weeks of initiating systemic treatment and tuberous xanthomas usually resolve after months, but tendinous xanthomas take years to resolve or may persist indefinitely.
The main goal of therapy for hyperlipidemia is to reduce the risks of atherosclerotic cardiovascular disease. In patients with severe hypertriglyceridemia, the goal is to prevent pancreatitis.