Is there any diabetic drug that will not cause stomach pain or upset stomach

Dear doctor .my grandmother has type 2 diabete for 10 years and she also has stomachace ,high blood pressure(high blood pressure i think it is caused by diabete) ,and heart valve damage (i think it is caused by Mediator drug ) .She use Amlor everyday to control high blood pressure.Sometime when she has stomuchache she take a drug which i dont remember the name .She used to take diamicron MR and it control her blood sugar .But now diamicron MR is useless  ,she has to have insulin injection every evening .Now her rountine is : taking diamicron MR in the morning and lunch and have insulin injection in evening .The reason she has to have insulin injection is that all other drugs upset her stomuch ( except diamicron MR ) .Doctor has prescribed her with Amaryl ,Glucophage ,Glucobay ,but they upset her stomuch .Although she take it after meal but she still have stomuch pain .So I want to ask what diabet drugs that don’t upset stomuch (because she hate to take insulin injection ).Thank you in advance

[WaveRider]

First, they are no doctors on this forum although we do get pseudo medical students dropping in from time to time. We are patients who volunteer our time to assist other patients.

"Although she take it after meal"
Normally this means as soon as she is finished eating, not waiting a few hours then taking them. Right? When a patient experiences stomach disturbance the next step is to take medication/s with meals. If it continues, discontinue use and notify the doctor.

There are six classifications of oral diabetes medications sold in the USA with several drugs listed under each. Amaryl and Diamicron MR are listed as Sulfonylureas yet appear to affect your grandmother differently. Everybody is different; one drug may cause discomfort in one patient yet it does not in another. Unless she is willing to experiment try to get her to understand which is easier for her at her age; injecting insulin or experimenting with drugs that may cause her an upset stomach or other worsening side effects.

[sakura411]

I forget to say that she is 85 years old

[WaveRider]

First, they are no doctors on this forum although we do get pseudo medical students dropping in from time to time. We are patients who volunteer our time to assist other patients.

"Although she take it after meal"
Normally this means as soon as she is finished eating, not waiting a few hours then taking them. Right? When a patient experiences stomach disturbance the next step is to take medication/s with meals. If it continues, discontinue use and notify the doctor.

There are six classifications of oral diabetes medications sold in the USA with several drugs listed under each. Amaryl and Diamicron MR are listed as Sulfonylureas yet appear to affect your grandmother differently. Everybody is different; one drug may cause discomfort in one patient yet it does not in another. Unless she is willing to experiment try to get her to understand which is easier for her at her age; injecting insulin or experimenting with drugs that may cause her an upset stomach or other worsening side effects.