Problem of GAD-ANTIBODY

[ajaypratibha1984]

I am 29 year old woman. Initialy I faced diabetic at the time of Pregnency in Oct 2005,thereafter it disappeared in Dec 2005. Later on in Sep2008 I was diagnosed Type II diabities.It is very fluctuating. I got further test whereas my GAD-ANTIBODY VALUE is coming 49.1 IU. ANTIBODY VALUE is coming 49.1 IU  /ml. Now a days I am taking T.Glynase MF & T.Galvus 50 MG for controlling of blood sugar two times before half an hour to meal.whether realy i am going to devlop type 1 diabities or else it can be controlled and will continue type II diabities.
How to get down the value of GAD65 . What should I do.

regards

Pratibha Chauhan

[WaveRider]

"whether realy i am going to devlop type 1 diabities or else it can be controlled and will continue type II diabities"

It is difficult to respond to your post fully when you left out key information.
1.) Your glucose levels - before and after meal
2.) GAD lab ranges - min to max. Lab ranges can vary from lab to lab especially when its country to country. See your copy of the lab test results for ranges.
3. Do you have normal weight, exercise regularly, and follow a good diabetic nutrition?

Additionally
1.) Have you had a C-Peptide test? (will give some indication of how much of your own insulin function remains)
2.) An A1c test? (how well you control/manage your glucose [blood sugar])

It should be noted that high anti-GAD antibody levels are considered markers for type 1 diabetes. When they occur in people who have what appears to be type 2 diabetes, it may indicate Latent-onset Autoimmune Diabetes of Adulthood (LADA aka Type 1.5 diabetes).
See this LADA explanation.
http://en.wikipedia.org/wiki/Latent_autoimmune_diabetes
Also these discussions on LADA
http://tinyurl.com/diabetes-lada

Are you seeing an Endocrinologist, a diabetes specialist? LADA is relatively new where many doctors do not recognize nor fully understand how to treat it.

The bottom line is that it matters most what you're doing is helping to control your diabetes.

[Zoelula]

There are a lot of misunderstandings in your post and you really should speak to an endocrinologist. Type II diabetes does not "turn into" Type 1, though some people (myself include) are initially misdiagnosed as Type II when they are in fact LADA/Type 1.5 or just Type 1. GAD antibodies, as Waverider says indicate Type 1 (or 1.5). They do not exist in Type IIs. You don't "reduce your GAD antibodies", all the GAD does is indicate type. If you have the antibodies and are type 1 or 1.5 you need to be on insulin not oral meds. Again, see an endo.

[ajaypratibha1984]

I am 29 year old woman. Initialy I faced diabetic at the time of Pregnency in Oct 2005,thereafter it disappeared in Dec 2005. Later on in Sep2008 I was diagnosed Type II diabities.It is very fluctuating. I got further test whereas my GAD-ANTIBODY VALUE is coming 49.1 IU. ANTIBODY VALUE is coming 49.1 IU  /ml. Now a days I am taking T.Glynase MF & T.Galvus 50 MG for controlling of blood sugar two times before half an hour to meal.whether realy i am going to devlop type 1 diabities or else it can be controlled and will continue type II diabities.
How to get down the value of GAD65 . What should I do.

As it was asked .

the details are as under

Today fasting glucose  level -186 mg/dl

post prandial plasama glucose- 148

The all other test was done on 09.09.2009 the these are

GAD lab range : Below 10.0IU/ml

whereas my GAD-ANTOBODY Value: 49.1 IU/ml
I am an almost normal weight person  Hight 156 cm weight 54 K.G but having the fat on tummy more than usual. I walk 40 minute daily
My C Peptide Value is  Fasting C-Peptide: .9 pmol/ml
                                  Stimulated C-Peptide : 2.0 pmol/ml

it was indicated in lab report fairly good Pacreatic Beta cell Reserve

An A1c test value is 8.4%

please suggest what should I do.

regards

Pratibha Chauhan

[WaveRider]

I don't know what your intentions were for opening these other two posts but you are creating confusion by having three posts on the same subject matter. We can follow you with just one.

Here's what is suggested.
1. Start a glucose [blood sugar] diary/log of EVERYTHING you eat and drink. Read about the Glycemic Index of foods. Avoid bad carbohydrates and starchy foods like potatoes. They turn into sugar after eaten.
2. Test before meals and 2-3 hours after a meal [postprandial].
3. If your postprandial glucose is above 10 mmol/l stop eating those foods. Too much sugar.
4. Speak with your doctor about an insulin pump and/or injectable insulin. Your A1c is very high.
5. Read about LADA [Latent Autoimmune Disease in Adults]. You may be a candidate. See this link http://tinyurl.com/aboutlada