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Diabetes - Adult Type II (Expert Forum)
Statins, Cystic Fibrosis & diabetes
Answered by
Anita Ramsetty, MD - GeneralEndocrinology, Diabetes Type 1, Diabetes Type 2, Thyroid Disorders, AdrenalInsufficiency, CF-Related Diabetes
Endocrine Care Group
Questions in the Adult Type II Diabetes forum are answered by Dr. Anita Ramsetty. Topics covered include Type 2 Diabetes, blood glucose monitoring, diabetes and heart disease, diabetes and pneumonia, diabetes and pregnancy,
diabetes and vision problems, diabetes and wound healing, diabetic complications, hyperglycemia, hypoglycemia, and insulin.
Statins, Cystic Fibrosis & diabetes
by Mary1994, Jul 30, 2008 03:52PM
Hi, I am CF, post dbl lung & kidney transplants, and taking lipitor (5mgQD) for prevention of chronic rejection, using its anti-inflammatory effects. I take it at night (HS). Breakfast sugars, taking 2 mg Prednisone, are harder to control & rise faster than remainder of day. Does lipitor have effects on the liver which impact the liver's release of glucogen?
This is without taking lexapro, advair, albuterol or other meds (excepting 2 mg prednisone) which would affect blood sugar. I asked about the lexapro previously ... still looking for an anti-depressive, SSRI or other, without adverse diabetic effects (to counter prograf-induced depression). Thank you for any insights.
This is without taking lexapro, advair, albuterol or other meds (excepting 2 mg prednisone) which would affect blood sugar. I asked about the lexapro previously ... still looking for an anti-depressive, SSRI or other, without adverse diabetic effects (to counter prograf-induced depression). Thank you for any insights.
Doctor's Answer
by Anita Ramsetty, MD, Aug 01, 2008 02:00PM
, Aug 01, 2008 02:00PM
Hi,
I do not Lipitor has hyperglycemic effects, as a general rule. The Prednisone, as you said, is the likely culprit. In addition, your own underlying insulin effects are still likely there because your own pancreas is in place, so the prednisone is likely exacerbating that effect.
Keep a close eye on everything and speak to your docs soon if you continue having sustained hyperglycemia. I am afraid it may mean another medication added on to control it, but the goal is to preserve you and your transplant so it may be needed.
Take care.
I do not Lipitor has hyperglycemic effects, as a general rule. The Prednisone, as you said, is the likely culprit. In addition, your own underlying insulin effects are still likely there because your own pancreas is in place, so the prednisone is likely exacerbating that effect.
Keep a close eye on everything and speak to your docs soon if you continue having sustained hyperglycemia. I am afraid it may mean another medication added on to control it, but the goal is to preserve you and your transplant so it may be needed.
Take care.
