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You're asking what it could do to you after you're taking it? You need to search each of the ingredients vs each of the medications to see if there any contradictions. For example; nopal vs glyburide contradictions. Don't believe the marketing hype about bitter melon for it doesn't mix well with metformin (Glucophage(R)), chlorpropamide (Diabinese(R)), glyburide (Diabeta(R) Glynase(R)), glipizide (Glucotrol(R)), insulin, and others).