Because (1) neuropathy may cause loss of sensation and the patient may not realize he has injured the foot by a cut or abrasion (2) there is a degradation of healing and in a diabetic such wounds become infected more easily (3) if the infection is not treated immediately, it may progress into the bone and tissue, requiring amputation of a toe, foot, or limb. Furthermore poor circulation in the feet makes oral antibiotics less effective in a diabetic.Treatment may have to be intravenously administered. These infections can progress rapidly, and only by a daily inspection of the foot can they be readily identified.
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