Cells in body

[Natliv]

Every cell in our body will die and body creates a new cell. Since every cell is recreated like this, the cells of organ will be replaced totally after some time. This depends upon the organ.

If this is the case, pancreas will be replaced after some time. Then why the replaced pancreas will not produce enough insulin? Is the problem with pancreas or something else?

[caregiver222]

Dr. Leonard Hayflick published a worthwhile book in 1994 titled "How and Why we age." (Ballantine books). The so-called "Hayflick number" was discovered in 1961. It represents the limit a normal human cell will divide before further cell division becomes impossible.. Every cell has a string of structures linked together somewhat like a shoelace consisting of what are called "telomeres". With each mitosis the telomere chain shortens by a certain amount. Telomeres have been called "The Clocks of Aging". Bacteria and cancer cells have no telomeres and are theoretically immortal. Curiously the cells of a few species (the alligator) also have no telomeres and are theoretically immortal. We have discovered a substance called telomerase that can cause an increase in the number of telomeres in vitro in the lab, but application to human aging is a long way down the road.

[Dee1956]

Natliv thank you for this question, interesting

[Dee1956]

Thank you for your post, very interesting
Dee

[Natliv]

Check the palm  and toes. If the entire cells are not replaced, these will be in rubbed condition. Even at older age, these  parts seem to be new. Every cells in our body have to be replaced after some time. Or otherwise how the organs will work for a long time?

[caregiver222]

The cells become damaged, and the damaged cells will, unfortunately, only reproduce with defects. In addition there is a limit to the number of replications possible in a human cell. That number is called the so-called Hayflick number, and this determines the mortality of the cell. There is a different number for every species. The Hayflick number is based upon the telomeres, a portion of which break off after every cell replication. So we have two "things" going on. First the normal "pattern" becomes distorted and the replicated cells cannot function in the same way as they should. And secondly there is a limit to the number of replications of a cell with an appropriate pattern.