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Clinical trial design
In the clinical trial design about obesity with type 2 diabetes , the exclusion criteria includes patients should be excluded if they have fasting glucose levels greater than 270 mg/dl, I wonder the the clinical significance of the 270 mg/dl? In the T2DM clinical guidance, I didn't find this value.  
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You will have to ask the people doing the trials.
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231441 tn?1333896366
Fasting levels of greater than 270, represent extremely poor control.   Patients with this fasting level likely have multiple complications.  I suspect this is why they would exclude people having these levels.
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Thanks for your help, I will search the related articles about the extremely poor control.
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