Tamoxifen increases liver function tests in 2% of cases. Regarding the return of cancer, if the CT scan and ultrasound are negative, it is less likely that the elevation is due to cancer.
You can do other tests - such as tests for hepatitis - but with the negative imaging tests and markedly elevated ALT/AST (into the triple digits), I agree that the liver biopsy is a reasonable next step. If the enzymes were below 100, waiting would be reasonable but the enzymes above 100, the biopsy is reasonable.
Followup with your personal physician is essential.
This answer is not intended as and does not substitute for medical advice - the information presented is for patient education only. Please see your personal physician for further evaluation of your individual case.
Thanks,
Kevin, M.D.
I agree you could have a CT scan of abdomen and have an AFP lab test to check for poss. tumor activity in liver. A CT or MRI would show something (ie liver cysts, or any poss. malignacy if there is any)...Hope it all looks OK.I am a nurse but also someone who has had scans of liver.
Good Luck
thanks bbmax, I am going to proceed with biopsy. I would rather be informed than not. Wish you well.
I too had elevated enzymes, it was caused my taking tylenol and having a couple of glasses of wine.
also, besides the tomxfin and glass of wine.... I got melenoma on my arm, in September, everything came out alright.