Hello,
I am a 31 year old male, about three weeks ago I noticed my eyes turned a slight yellow. This prompted me to see my physician. My lab test showed an ALT of 2400, an AST of 1300 and a direct billirubin of 6.2, and an indirect of 10.2. At this point I had not had an alcoholic beverage for 2 weeks. It is also worth mentioning that I do not take any over the counter or prescription medication - including Acetaminophin. A repeat of the ALT 5 days later showed 2000. All other liver function and CBC tests were normal. I also underwent a CT scan of the liver and spleen, the liver was negative, and my spleen was mildly elarged. I was referred to a Gastro Intestinal Specialist, and more tests are underway, including auto immune, Wilson's, and a few others. I have tested negative for hep A, B, and C. I was a heavy drinker for approx. 10 years, probably close to daily the past 5 years, but haven't drank for the past 4 weeks. Ironically, I quit drinking permanenlty one week prior to noticing any liver symptoms. Prior to this time I have not experienced any symptoms of any kind of disease or problems. I feel fine, other than not knowing what is going on in my liver. I am not scheduled to see my specialist for another 3 weeks, and in the mean time, he has ordered once a week LFPs.
My questions are:
1. Can alcohol abuse lead to liver enzymes that high? Especially after 2 weeks of abstinence prior to my first blood test?
2. Can alochol give an AST:ALT ratio of approx. 0.5?
3. With enzymes this high are my chances high for the development of fibrosis/scarring leading to cirrhosis even with permanent abstinence?
Thanks for your time.