To my knowledge, ulcers aren't hereditary unless you have a tumor which is secreting too much acid and they would have picked this up with an upper GI series or endoscope. Not all ulcers are H. pylori related. Bleeding ulcers are typical of alcoholics, people under high stress, people using excessive motrin/naprosyn/aspirin etc. The carafate may be affecting the absorption of the nexium...as your pharmacist, you doc probably didn't realize this. YOu can use maalox with the nexium or zantac with the nexium for several wks to increase the effects. Stay away from caffinated products and spicey foods and the medications I noted. NO alcoholic beverages either. Hope you enjoy your holidays
KJK
I have peptic ulcer disease also with none of the risk factors (no H. pylori, no asprin use, no alcohol,...). My father and 3 grandparents had tummy troubles so I think there may be an inherited link. Previcid works for me as well as avoiding certain foods (peppermint anything, fizzy drinks, cough suppressants,...). You probably know by now what makes your symptoms worse and what to avoid. Have you been tested for Zollenger-Ellison syndrome (acid-secreting tumors)? I used to try to ignore the burning pain for the longest time but have found now that if I start treatment right away, the ulcers heal relatively fast. I've found that eating small, frequent meals helps keep the acid neutralized. I'm sorry for your condition but am relieved to know there are a few others out there with no known cause for ulcer disease.
I would suggest using the Nexium only. I take two x 20mg pills a day. I find that if I take them just before sitting down to eat I get the best balance between side effects and effectiveness.
I have had biopsies and blood tests for HP and they all came back negative. I never drank alcohol before or after I got ill and I never used Aspirin either. I've always had a healthy diet and I was not even remotely stressed at the time I got ulcers. I had the Antibiotic treatment for HP and that made no difference.
I found that Carafate made my symptoms worse. I asked my Doc for Carafate as I had read about it on the web but he said that it's not prescibed that often anymore (here in England) as it is only of limited effectiveness compared to PPI's etc. Apparently the drug went out of fashion many years ago. I believe that your pain is probably caused by the carafate preventing the Nexium from working as opposed to visa versa.
Don't listen to anyone that recommends DGL. I tried it and that too made my symptoms worse and I even developed mouth ulcers for the first time in my life!!! PPI's are the most effective treatment around apart from having part or all of your stomach removed so give them a chance. I also find that keeping some food in my stomach helps alot. Ive put on a bit of weight from constantly eating but it's better than the alternative!
The Docs can't offer an explanation as to why I started getting ulcers but they started at exactly the same time that I got Mono. I don't believe that is a coincidence. They thought I was faking at first and said that I just had IBS! They didnt believe me until they did the endoscopy and saw the damage with their own eyes! If you ever find out the cause of your ulcers be sure to let me know!
I posted a question on the WebMD site last week. Here is a link to an article that I was directed to regarding the H. Pyloria Bacteria. Hope this information helps you.
http://my.webmd.com/content/article/6/1680_51118.htm?lastselectedguid={5FE84E90-BC77-4056-A91C-9531713CA348}
To KJK - Have no fear, I do not drink so that is definitely not my problem. My fathers bleeding ulcers were definitely caused by his drinking. I've been told by other people that when they have taken the Carafate their doctors told them NOT to take the Nexium. All I know is when I take the two together my stomach hurts worse than it otherwise would. Thank you for your concerns. You have a WONDERFUL HOLIDAY!!!
HAVE KNOWN PEOPLE WHO TOOK R-E-C-L-U FOR ULCERS, AND ALSO PEPPERS HELPED, UNUSUAL BUT TRUE, NEXIUM WORKED FOR ME BUT I ONLY HAD OCCASIONAL REFLUX.
I am sorry I don't have words of wisdom to help out, but I have heard this H. Pylori Bacteria quite a bit lately. In fact I have to take a friend this week for her test. Can you tell me what it is. Sure hop the meds start taking effect and it works for you.
Thanks,
Dejsa