Posted By HFHSM.D.-rf on January 30, 1998 at 22:39:26:
In Reply to: Use of loperamide posted by Michael on January 25, 1998 at 17:43:01:
: Dear sirs, I am a 31 year old male who had a colectomy and ileoanal j-pouch
surgery in 1993. This was due to severe colitis. I find that when I use
loperamide it lessens the frequency of bowel movements and I generally use
it if I know I will be in a situation where bathrooms aren't very accessable.
I've been trying to find out what kind of dosages are safe for extended
periods of time. Getting up 2-3 times a night to use the bathroom is a real
pain in the neck and I rarely get a good night's sleep. However, if it is
safe to do so, I would love to be able to take perhaps 1 2mg pill a day to
help me sleep at night, but I'm not going to try this until I have some real
evidence that it would be ok. If you know, or could point me in the right
direction to someone who does, I would be eternally grateful.
Thank you, Michael Basta
Dear Michael Basta
Patients who have had a colectomy and ileoanal anastomosis often have an increased frequency of defecation of soft or usually liquid stool. The diarrhea results from the loss of the colon. Under normal circumstances approximately 600 ml of fluid enters the colon from the small intestine. Most of this fluid is absorbed in the colon and approximately only 200 ml of stool is passed per day. After the colon has been removed, however, this absorptive capacity is lost and whatever fluid leaves the small intestine is passed as feces.
Using loperamide is safe and often effective treatment to relieve the diarrhea associated with colon removal. Taking loperamide before going to sleep should allow for a restful night. In fact, loperamide can be used on a regular basis, so that you are able to perform your regular daytime activities, without the constant fear of diarrhea and incontinence. For chronic diarrhea, you can start with a loperamide dosage of 1 tablet 2 or 3 times a day. You can adjust the dosage (up or down) in order to obtain the frequency of defecation that you find acceptable. You should not use more than 8 pills per day without consulting with your physician. Some patients are very sensitive to the effects of loperamide and are well controlled with only 1 pill/day. You will learn your requirements as you gain experience with the medication.
Although the bowel pattern that you describe may be the result of your colon resection, there are other diagnostic considerations. 1)
The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. Med Help International, Inc. is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. Never disregard the medical advice of your physician or health professional, or delay in seeking such advice, because of something you read on this Site. We offer this Site AS IS and without any warranties. By using this Site you agree to the following Terms and Conditions. If you think you may have a medical emergency, call your physician or 911 immediately.