I am a 30 year old female with a known autoimmune disorder psoriasis and psoriatic arthritis. Tests were done to determine if bowel symptoms were cause of arthritis symptoms. Over the last 6 months to a year I have experienced intermittent diarrhea and rectal bleeding as well as occasional abdominal cramping. Bright red rectal bleeding can occur without BM and can turn water red. Hgb dropped from 14.3 to 12.9 over 10 days. Most recent episode experienced diarrhea, bleeding, fever, severe cramping, weight loss, arthritis pains and anorexia. Initial stool cultures were negative. Diarrhea contains mucus but no blood. From recent symptoms of ongoing bleeding, it seems more related to a fissure rather than hemorrhoids and Anusol HC does not help with bleeding or irritation.
Colonoscopy revealed mild proctitis and grade I hemorrhoids. Cultures done at time of colonoscopy came back positive for campylobacter, greater than two weeks after initial onset. Histology report diagnosis--Fragments of colon mucosa with moderate nonspecific inflammation, random colon biopsies. Microscopic evaluation--Sections show pieces of colon mucosa with moderate lymphoplasmacytic infiltration of lamina propria. Significant crypt distortion is not identified. Thickening of collagen band or transmucosal inflammation is absent. Occasional reactive lymphoid aggregates are present.
Abdominal symptoms worsen with menstrual cycle, stress, and caffeine intake. Oral prednisone resolves arthritis pain and lessens GI symptoms. Cannot treat arthritis/psoriasis until determine cause of GI complaints. Cannot take sulfa medications or NSAIDs
What exactly is chronic nonspecific colitis?
How is it treated?
Can it cause arthritis pain in back, wrists, elbows, knees, ankles, and fingers?
If due to a fissure, how to stop diarrhea related to this to prevent further tearing and blood loss?
What is treatment for campylobacter?
Thanks for your help.