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WHY DOWN?

It it proved that women over 35 are more risked to have Down babies. why does that happen?
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Have any of you heard the story of Michelle Desrocher?  Very interesting.
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1227139 tn?1462334630
Hello Christin93,

This question is asked a lot of the time.  The actual reality is, more babies with Down syndrome are born to women between the ages of 20-30 simply because this age group bears more children, and thus will have more numbers of children with Ds more often.  However, the reason why it is more statistically a risk to have a child with Ds after the age of 35 is not completely clear.  Only that science has noted that it does occur more often statistically to women over the age of 35.  The thought behind this is that the instructions from the ova (egg from the woman) become more cloudy.  In this you must understand what Down syndrome (Ds) or Trisomy 21 actually is.  Ds happens at conception.  At the moment of conception, each parent provides a copy of each of their 23 chromosomes to total 46 to the offspring.  For an unknown reason, the 21st chromosome gets a triplicate instead of a pair and the offspring ends up with three copies of the 21st chromosome.  It is unknown which parent provided the offspring with the extra copy but the fact is as the mother ages, the instructions to pass only one copy of each chromosome is less clear and it seems that when the maternal eggs are older the possibility of a trisomy is more likely to occur.  It doesn't mean that the mother is the one responsible for passing the extra copy on to the baby, it just means that the instructions to pass on one copy doesn't happen and either mother or father pass on both copies of their 21st chromosome.

I have a brand new website with the answers to this very question and all the resources anyone could hope for with respect to Down sydnrome.  It should be ready soon, but in the mean time, everyone is welcome to visit my blog http://welcometoourhouse-myjournal.blogspot.com

If you have any other questions about Down syndrome, please feel free to ask me at any time.  I do answer a lot of questions for school assignments and university studies.

In addition to anything I have mentioned, please keep in mind, that while I or others may have extensive knowledge in many areas, you should always seek professional medical advice from your own physician, as it pertains to medical conditions or concerns.

Good luck, and if you have any other questions that I can help you with, please feel free to message me directly.

Sincerely,
Sandi (Dragon1973)
MedHelp Genetics Community Leader;
Children - Special Needs Community Leader;
Down syndrome Community Leader & Ds Group Forum Founder/Moderator
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