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POTS and Venlafaxine

Hi everyone :-)

I saw my GP today, who decided that I should try Venlafaxine (SSNRI).

I currently take Midodrine 10mg 4x day, and Desmopressin 0.2 mg 1x day, with minimal effect, as my HRs are still all over the place, and no real abatement in my other dysautonomia symptoms.

Dr Grubb advised SSNRI in his pharmacological treatment, hence my GP wanting to try it.

So my question is - Has anybody tried it to control POTS symptoms? Has it worked?

Any input would be appreciated.

Thanks.
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Avatar universal
Thank you both for your input :-)

Very much appreciated, and thank you for the warning, annesf.
Helpful - 0
Avatar universal
Hi-
I am on 225 mg of venlafaxine for POTS.  I haven't noticed any reduction of my POTS symptoms, but I haven't had any obvious side effects so I have stayed on it in hopes that I will find an addition drug/supplement that may work with the venlafaxine to reduce my fatigue and other POTS symptoms.
I want to warn you, though, that getting on venlafaxine is not too hard, but getting off of it is very difficult.  I was on it years ago for depression and the withdrawal symptoms took me about a month to get through.
Helpful - 0
875426 tn?1325528416
I tried Effexor for only three days when it was given to me to treat migraines and I couldn't tolerate the side effects.   Don't remember now what all they were- just that it was intolerable for me.  It wasn't given to me for POTS- it was before I was diagnosed with POTS I tried it.
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