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My Mom and I used Afrin around Thanksgiving 2007. To date, neither one of us can smell or taste much of anything. Has your smell and taste returned? We have both been to several doctors and none can find anything wrong. They claim it is not the Afrin, but how do they know? We are looking for others with the same problem and asking if you have found a solution.
I used Afrin spray about three years ago when I had a bad cold. I didn't read the directions very well and over used it. Ever since then, I constantly have to blow my nose. It drains every morning causing me to cough. I went to my doctor and they tried treating me for allergies. I never had an issue with allergies in the past. When nothing worked, I gave up and thought it would just go away. It didn't. I have noticed that I can't smell things as well as I used to. I personally believe I may have damaged my nose using this spray. I regret ever picking it up off the shelf. I have thought about seeing a nose and throat specialist, but am afraid of the costs that might add up to. This may be the only way to go about it. My doctor did say my septim was swollen. That is why they thought allergies, but I tried everything out there for that and none worked. The lack of smell may be causing issues with your taste buds, but I bet the problem is your nose.
I have used Afrin for two days now (original formula) and I can not smell or taste ANYTHING AT ALL. I found you by doing a search to see if anyone else has had the same problem. I hope it goes away when it wears off, but after reading your post (and literally being unable to taste or smell even 12 hours after the last dose) I'm worried it may be more permanent. Will keep you posted.