Epilepsy Community
Seizure medication dosage
About This Community:

This patient support community is for discussions relating to epilepsy, safety, school issues, and transportation issues.

Font Size:
A
A
A
Background:
Blank
Blank
Blank
Blank Blank

Seizure medication dosage

Hi my daughter 15 years old, 88 lbs is on valproate sodium 10 mL twice daily and rivotril 0.5 mg two tabs daily. What is the optimum dosage for her as she still continues with sudden mood swings from normal to suddenly laughing or crying, which as per neurosurgeon are nothing but small scale seizures. Thanks
Avatar_dr_f_tn
Hello,
Usually valproate is initiated at a dosage of 10 to 15 mg/kg/day. The dose is increased gradually by 5 to 10 mg/kg/week to achieve optimal clinical response. Usually optimal clinical response is achieved at daily doses below 60 mg/kg/day. If there is no satisfactory clinical response determination of plasma levels to check whether they are in therapeutic range (50 to 100 µg/mL) or not should be done. It is usually not recommended to take valproate at doses above 60 mg/kg/day .Emotional lability is one of the side effects of valproate.It is best to have  a frank discussion with your doctor and get your doubts clarified. Do keep us posted.
Take care and regards!
Blank
Post a Comment
To
Recent Activity
Avatar_f_tn
Blank
mkh9 Finally cooler in San Diego! Comment
22 hrs ago
Avatar_f_tn
Blank
mkh9 commented on mkh9's status
Aug 28
1780921_tn?1416842066
Blank
flipper336 "Every morning we are born ... Comment
Aug 22
Top Neurology Answerers
293157_tn?1285877039
Blank
Wobbly
1780921_tn?1416842066
Blank
flipper336
Chandler, AZ
Epilepsy Community Resources
RSS Expert Activity
233488_tn?1310696703
Blank
Marathon Running Done Over Many Yea...
May 21 by John C Hagan III, MD, FACS, FAAOBlank
233488_tn?1310696703
Blank
New Article on Multifocal IOL vs &q...
May 21 by John C Hagan III, MD, FACS, FAAOBlank
748543_tn?1371753642
Blank
TMJ/TMJ The Connection Between Teet...
Jan 27 by Hamidreza Nassery , DMD, FICOI, FAGDBlank
Top Neurology Answerers
293157_tn?1285877039
Blank
Wobbly
1780921_tn?1416842066
Blank
flipper336
Chandler, AZ