Aa
A
A
Close
Avatar universal
Seizure medication dosage
Hi my daughter 15 years old, 88 lbs is on valproate sodium 10 mL twice daily and rivotril 0.5 mg two tabs daily. What is the optimum dosage for her as she still continues with sudden mood swings from normal to suddenly laughing or crying, which as per neurosurgeon are nothing but small scale seizures. Thanks
Cancel
1 Answers
Page 1 of 1
Avatar universal
Hello,
Usually valproate is initiated at a dosage of 10 to 15 mg/kg/day. The dose is increased gradually by 5 to 10 mg/kg/week to achieve optimal clinical response. Usually optimal clinical response is achieved at daily doses below 60 mg/kg/day. If there is no satisfactory clinical response determination of plasma levels to check whether they are in therapeutic range (50 to 100 µg/mL) or not should be done. It is usually not recommended to take valproate at doses above 60 mg/kg/day .Emotional lability is one of the side effects of valproate.It is best to have  a frank discussion with your doctor and get your doubts clarified. Do keep us posted.
Take care and regards!
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Comment
Post Comment
Your Answer
Avatar universal
Answer
Do you know how to answer? Tap here to leave your answer...
Answer
Answer
Post Answer
A
A
Recent Activity
1415174 tn?1453246703
Blank
mkh9 When you've been knocked do... Comment
Nov 22
1415174 tn?1453246703
Blank
mkh9 uploaded new photos
Oct 10
Avatar universal
Blank
zahidkapariya commented on photo
Oct 10
Top Neurology Answerers
144586 tn?1284669764
Blank
1780921 tn?1462244109
Blank
Queen Creek, AZ
Epilepsy Community Resources