EBV lab results.. PLEASE HELP>>

[skarey]

I was tested for EBV and here are my labs.  My dr didn't tell me anything beside that I've had EBV in the past (which I didn't know).  Here are my labs..    What does this mean?

EBV CAP IGG..............POSITIVE              H                 (NEGATIVE)
EBV CAP IGM..............NEGATIVE                                (NEGATIVE)
EBNA IGG...................POSITVE               H                 (NEGATIVE)

Interpretations:
EBV SWEROLOGICAL STATUS              EBV IgM               EBV IgG  VCA                EBV NA IgG
Primarey acute                                        POS                          NEG                               NEG
Late Acute                                              POS                          POS                               NEG
Late Acute                                              POS                          POS                               POS
Convalescent/previous inf.                        NEG                          POS                               NEG
Previous Infection                                    NEG                          POS                               POS

Follow up testing recommended.  

  HELP PLEASE!!!  i dON'T GET THIS!

[PlateletGal]

This may help your physician rule out Chronic Fatigue Immune Dysfunction Syndrome. For additional tests, visit:

http://www.medhelp.org/health_pages/Fibromyalgia/Diagnostic--Blood-Tests-to-Help-Diagnose-CFS/show/376?cid=39


Most patients with CFS usually have 2 or 3 of the following abnormalities:

Elevated IgM/IgG coxsackievirus B titer
Elevated IgM/IgG HHV-6 titer
Elevated IgM/IgG C pneumoniae titer
Decreased NK cells, either the percentage or their activity

http://emedicine.medscape.com/article/235980-diagnosis

[PlateletGal]

Here is a better website on interpreting EBV test results (as confusing as it is).

Read where it says, "what does the test result mean"?

http://www.labtestsonline.org/understanding/analytes/ebv/test.html

[m300]

Why didnt your practicioner test the EBV EA (Early Antigen)?  This tells if the virus is active in most people.

PlateletGal is right - most family doctors don't know how to read EBV antibody labs.  Mine sure can't.  Find a good rhuematologist or infectious disesase dr.

[skarey]

Just realized that it showed up wrong above.  Disregard that one.  Here is how the lab read...

Just noticed that the above was wrong.  Disregard it....  Here is what it read...

EBV CAP IGG..............POSITIVE              H                 (NEGATIVE)
EBV CAP IGM..............NEGATIVE                                (NEGATIVE)
EBNA IGG...................POSITVE               H                 (NEGATIVE)

Interpretations:
EBV Serological Status     EBV IgM        EBV IgG VCA     EBV NA IgG

Primary Acute                   POS                 Neg                    NEG
Late Acute                        POS                 POS                   NEG
Late acute                         POS                 POS                   POS
convalescent/previous inf.   NEG                 POS                    NEG
previous infection               NEG                 POS                   POS

Follow up testing recommended

WHAT DOES THIS MEAN?

[PlateletGal]

source: http://www.cdc.gov/ncidod/diseases/ebv.htm

[PlateletGal]

Sorry... I can't really help you interpret EBV results. I don't think many physicians can either. All I know is that if your IgM is positive... that shows a recent or current infection. If your IgG is positive, that shows a past infection.

Here is what the CDC has to say on testing (more confusion):


SUMMARY OF INTERPRETATION

The diagnosis of EBV infection is summarized as follows:

Susceptibility
If antibodies to the viral capsid antigen are not detected, the patient is susceptible to EBV infection.

Primary Infection
Primary EBV infection is indicated if IgM antibody to the viral capsid antigen is present and antibody to EBV nuclear antigen, or EBNA, is absent. A rising or high IgG antibody to the viral capsid antigen and negative antibody to EBNA after at least 4 weeks of illness is also strongly suggestive of primary infection. In addition, 80% of patients with active EBV infection produce antibody to early antigen.

Past Infection
If antibodies to both the viral capsid antigen and EBNA are present, then past infection (from 4 to 6 months to years earlier) is indicated. Since 95% of adults have been infected with EBV, most adults will show antibodies to EBV from infection years earlier. High or elevated antibody levels may be present for years and are not diagnostic of recent infection.

Reactivation
In the presence of antibodies to EBNA, an elevation of antibodies to early antigen suggests reactivation. However, when EBV antibody to the early antigen test is present, this result does not automatically indicate that a patient's current medical condition is caused by EBV. A number of healthy people with no symptoms have antibodies to the EBV early antigen for years after their initial EBV infection. Many times reactivation occurs subclinically.

Chronic EBV Infection
Reliable laboratory evidence for continued active EBV infection is very seldom found in patients who have been ill for more than 4 months. When the illness lasts more than 6 months, it should be investigated to see if other causes of chronic illness or CFS are present.