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SGOT and,SGPT
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SGOT and,SGPT

what is the meaning of SGOT and SGPT
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Avatar_f_tn
Hi,
     How are you? Alanine aminotransferase (ALT), formerly called serum glutamate pyruvate transaminase, or SGPT, is an enzyme necessary for energy production. It is present in a number of tissues, including the liver, heart, and skeletal muscles, but is found in the highest concentration in the liver. Because of this, it is used in conjunction with other liver enzymes to detect liver disease, especially hepatitis or cirrhosis without jaundice. Additionally, in conjunction with the aspartate aminotransferase test (AST), it helps to distinguish between heart damage and liver tissue damage.

Aspartate aminotransferase (AST), formerly called serum glutamic-oxaloacetic transaminase, or SGOT, is another enzyme necessary for energy production. It, too, may be elevated in liver and heart disease. In liver disease, the AST increase is usually less than the ALT increase. However, in liver disease caused by alcohol use, the AST increase may be two or three times greater than the ALT increase.

Normal values are:

ALT or SGPT: 5-35 IU/L
AST or SGOT: 0-35 IU/L

Consult your physician for further assistance.
Best.
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Avatar_m_tn
hi Dr,
My SGPT is 259 U/l and SGOT is 117 U/l in my recent test . How to bring it down?
what it indicate, since last 7-8 years both of the enzyme were in  higher side. does this figure is really to be worried? please reply. Thanks
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