how do you lose muscle?

Is it possible to lose muscle in one area?
I need to lose muscle in my thighs, because they are HUGE, but i don't know how to. The more running and strength training i do just makes them look bigger. People always say toning is supposed to make things look more cut and nicely shaped, but my thighs still look like blobs, even though they are firm. Maybe i'm not doing it right?
So How? i don't want to lose muscle anywhere else though. Is this possible?
Is losing muscle the same as weight loss? Because i can't afford to lose any more weight.
It's strange, my body is very, very lean, but my thighs are massive.

[Dr Vinod]

Hello!

You have to first distinguish the fat from muscle in your thighs.

Fat can get deposited at various areas depending on your genetic built and remember the fat which gets deposited first will be the last to dislodge.

With exercise and physical activity and regular cardio your muscles get toned and it is very difficult to comment without examining you as massive muscle building at only the thigh region is rare.  

Get yourself examined by a GP/Orthopedician to diagnose and guide you properly.

Take care!