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GOOD DIET LOWER RISK OF MACULAR DEGENERATION
NEW JOURNAL STUDIES
High antioxidant intake may lower early AMD risk in genetically predisposed patients
Investigators assessed the intake of antioxidants, zinc, and ω-3 fatty acids in daily foods among 2,167 individuals 55 years or older who were at risk for AMD and enrolled in the Rotterdam Study. Participants completed a semiquantitative food frequency questionnaire at baseline and underwent genetic testing. At about eight years follow-up, they found a possible biological interaction between the CFH Y402H genotype and intakes of zinc, β-carotene, lutein/zeaxanthin, and eicosapentaenoic/docosahexaenoic acid (EPA/DHA), and between the LOC387715 A69S genotype and zinc and EPA/DHA, based on significant synergy indices (P < .05 for all). Archives of Ophthalmology, June 2011
High antioxidant intake may lower early AMD risk in genetically predisposed patients
Investigators assessed the intake of antioxidants, zinc, and ω-3 fatty acids in daily foods among 2,167 individuals 55 years or older who were at risk for AMD and enrolled in the Rotterdam Study. Participants completed a semiquantitative food frequency questionnaire at baseline and underwent genetic testing. At about eight years follow-up, they found a possible biological interaction between the CFH Y402H genotype and intakes of zinc, β-carotene, lutein/zeaxanthin, and eicosapentaenoic/docosahexaenoic acid (EPA/DHA), and between the LOC387715 A69S genotype and zinc and EPA/DHA, based on significant synergy indices (P < .05 for all). Archives of Ophthalmology, June 2011
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