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Now assuming you are seeing an Eye MD I have no idea why patanol would help as it is a drop for allergy.
You need a corneal topography and a trial fitting of rigid gas permeable contacts to rule out irregular astigmatism as the cause of your problem.
I can't emphasize enough that if you are seeing an "OD" instead of a "MD" then you hae not really been properly examined. You can find an eye MD at www.aao.org
JCH IIIIMD
Interesting that yours occurs when you're tired. ME TOO--in fact, although normally my ghosting occurs after reading looking down, it will occur spontaneously when I'm very tired (sleep-deprived).
I don't understand why that would be the case if it's a corneal problem.
My opthalmologist also told me that my astigmatism was not sufficient to be causing this problem.
I did not have any tests such as corneal topography.
Good luck getting to the bottom of things, and please let us know what you find out.
I do have various other odd symptoms, was told MS at one point, then told it's not. However, the neurologists never knew about the ghosting thing, since it started after I was through with the neuros (or they were through with me).
Nancy T. (51 years old, ghosting began maybe 5 years ago)