Anion Gap result

Received a blood test through Health Quest at work that showed Anion Gap Range of 2 mmol/L this year and last year was 7 mmol/L Reference Range should be between 5-16.  Should I wait another year to see if it changes again?  I am not sure if this is good bad or nothing to be concerned about?

[Kevin Pho, MD]

The anion gap is simply the result of the following formula:
AG = Serum Sodium - Serum Chloride - Serum Bicarbonate

Here are some causes of a low anion gap:

# Paraproteinemia (Multiple Myeloma)
# Spurious Hyperchloremia (Bromide toxicity)
# Hyponatremia (low sodium level)
# Hypermagnesemia (high magnesium level)
# Hypoalbuminemia (low albumin level)

You may want to discuss with your physician further tests to evaluate the aforementioned conditions.

Followup with your personal physician is essential.

This answer is not intended as and does not substitute for medical advice - the information presented is for patient education only. Please see your personal physician for further evaluation of your individual case.

Thanks,
Kevin, M.D.

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