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Family Medicine (Expert Forum)
A CBC TEST SHOWED LOW WBC/NEUTROPHIL COUNTS
Answered by
Kevin Pho, MD - Internal Medicine
KevinMD.com
Questions in the Family Medicine forum are answered by Dr. J.M. Keyes. Topics covered include general health issues, adolescence, babies, child health, eating disorders, fitness, immunizations and vaccines, infectious diseases, medical tests and procedures, and senior health.
A CBC TEST SHOWED LOW WBC/NEUTROPHIL COUNTS
by EJIMOGU, Sep 30, 2004 12:00AM
When I was in Africa,I had typhoid AND was TAKING CHLOROPHENICOL FOR TREATMENT.I was on this drug for over two years taken as sypmtoms appear.I moved to the US 7 YEARS AGO.A CBC TEST RESULT SHOWS THAT MY WBC IS 3.4 L AND MY NEUTOPHIL 1295 L. I went for bone marrow biopsy and nothing was found. COULD THE CHLOROPHENICOL BE THE CAUSE FOR THE LOW VALUES. What is the best treatment ? COULD NEUPOGEN DRUG BE USEFUL TO ME?
ROBERT
ROBERT
Doctor's Answer
by Kevin Pho, MD, Oct 02, 2004 12:00AM
, Oct 02, 2004 12:00AM
Chloramphenical can cause a low white cell count and aplastic anemia. However, it is normally reversible after discontinuing the medication, and it is unlikely that it would be the cause in your case.
First thing would be to find the cause. A test for HIV should certainly be considered. Tests to determine the presence of neutrophil antibodies, an ANA test looking for collagen vascular disease, immunoglobulin tests looking for defects in cellular immunity, as well as tests for vitamin B12 should all certainly be considered.
Before considering treatment, I certainly would have further evaluation with a hematology referral.
Followup with your personal physician is essential.
This answer is not intended as and does not substitute for medical advice - the information presented is for patient education only. Please see your personal physician for further evaluation of your individual case.
Kevin, M.D.
Medical Weblog:
kevinmd_b
First thing would be to find the cause. A test for HIV should certainly be considered. Tests to determine the presence of neutrophil antibodies, an ANA test looking for collagen vascular disease, immunoglobulin tests looking for defects in cellular immunity, as well as tests for vitamin B12 should all certainly be considered.
Before considering treatment, I certainly would have further evaluation with a hematology referral.
Followup with your personal physician is essential.
This answer is not intended as and does not substitute for medical advice - the information presented is for patient education only. Please see your personal physician for further evaluation of your individual case.
Kevin, M.D.
Medical Weblog:
kevinmd_b
http://www.livingfirstclass.com/doctor.html